His Bundle and Left Bundle Pacing with Optimised Atrio-ventricular Delay Achieve Superior Electrical Synchrony over Endocardial and Epicardial Pacing in Left Bundle Branch Block Patients.
Strocchi M, Lee AWC, Neic A, Bouyssier J, Gillette K, Plank G, Elliott MK, Gould J, Behar JM, Sidhu B, Mehta V, Bishop MJ, Vigmond EJ, Rinaldi CA, Niederer SA (2020) Heart Rhythm, In Press.
PMID: 32603781, DOI: 10.1016/j.hrthm.2020.06.028

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.
Strocchi M, Augustin CM, Gsell MAF, Karabelas E, Neic A, Gillette K, Razeghi O, Prassl AJ, Vigmond EJ, Behar JM, Gould J, Sidhu B, Rinaldi CA, Bishop MJ, Plank G, Niederer SA (2020) PLoS One, 15(6): e0235145.
PMID: 32589679, DOI: 10.1371/journal.pone.0235145

Personalization of electro-mechanical models of the pressure-overloaded left ventricle: fitting of Windkessel-type afterload models.
Marx L, Gsell MAF, Rund A, Caforio F, Prassl AJ, Toth-Gayor G, Kuehne T, Augustin CM, Plank G (2020) Philos Trans A Math Phys Eng Sci, 378(2173): 20190342.
PMID: 32448067, DOI: 10.1098/rsta.2019.0342

Creation and application of virtual patient cohorts of heart models.
Niederer SA, Aboelkassem Y, Cantwell CD, Corrado C, Coveney S, Cherry EM, Delhaas T, Fenton FH, Panfilov AV, Pathmanathan P, Plank G, Riabiz M, Roney CH, Dos Santos RW, Wang L (2020) Philos Trans A Math Phys Eng Sci, 378(2173): 20190558.
PMID: 32448064, DOI: 10.1098/rsta.2019.0558

The impact of wall thickness and curvature on wall stress in patient-specific electromechanical models of the left atrium.
Augustin CM, Fastl TE, Neic A, Bellini C, Whitaker J, Rajani R, O'Neill MD, Bishop MJ, Plank G, Niederer SA (2020) Biomech Model Mechanobiol, 19(3): 1015-1034.
PMID: 31802292, DOI: 10.1007/s10237-019-01268-5

Direct comparison of a novel antitachycardia pacing algorithm against present methods using virtual patient modeling.
Swenson DJ, Taepke RT, Blauer JJE, Kwan E, Ghafoori E, Plank G, Vigmond E, MacLeod RS, DeGroot P, Ranjan R (2020) Heart Rhythm, In Press.
PMID: 32438017, DOI: 10.1016/j.hrthm.2020.05.009

Left ventricular endocardial pacing is less arrhythmogenic than conventional epicardial pacing when pacing in proximity to scar.
Costa CM, Neic A, Gillette K, Porter B, Gould J, Sidhu B, Chen Z, Elliott M, Mehta V, Plank G, Rinaldi CA, Bishop MJ, Niederer SA (2020) Heart Rhythm, In Press.
PMID: 32272230, DOI: 10.1016/j.hrthm.2020.03.021

3D Electrophysiological Modeling of Interstitial Fibrosis Networks and Their Role in Ventricular Arrhythmias in Non-ischemic Cardiomyopathy.
Balaban G, Mendonca Costa C, Porter B, Halliday B, Rinaldi CA, Prasad S, Plank G, Ismail TF, Bishop MJ (2020) IEEE Trans Biomed Eng, In Press.
PMID: 32275581, DOI: 10.1109/TBME.2020.2976924

Computational modeling of cardiac growth and remodeling in pressure overloaded hearts-Linking microstructure to organ phenotype.
Niestrawska JA, Augustin CM, Plank G (2020) Acta Biomater, 106: 34-53.
PMID: 32058078, DOI: 10.1016/j.actbio.2020.02.010

Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium.
Strocchi M, Gsell MAF, Augustin CM, Razeghi O, Roney CH, Prassl AJ, Vigmond EJ, Behar JM, Gould JS, Rinaldi CA, Bishop MJ, Plank G, Niederer SA (2020) J Biomech, 101: 109645.
PMID: 32014305, DOI: 10.1016/j.jbiomech.2020.109645

Versatile stabilized finite element formulations for nearly and fully incompressible solid mechanics.
Karabelas E, Haase G, Plank G, Augustin CM (2020) Comput Mech, 65(1): 193-215.
PMID: 31975744, DOI: 10.1007/s00466-019-01760-w

Automating image-based mesh generation and manipulation tasks in cardiac modeling workflows using Meshtool.
Neic A, Gsell MAF, Karabelas E, Prassl AJ, Plank G (2020) SoftwareX, 11: 100454.
PMID: 32607406, DOI: 10.1016/j.softx.2020.100454


Factors Promoting Conduction Slowing as Substrates for Block and Reentry in Infarcted Hearts.
Campos FO, Whitaker J, Neji R, Roujol S, O'Neill M, Plank G, Bishop MJ (2019) Biophys J, 117(12): 2361-2374.
PMID: 31521328, DOI: 10.1016/j.bpj.2019.08.008

Inverse localization of earliest cardiac activation sites from activation maps based on the viscous Eikonal equation.
Kunisch K, Neic A, Plank G, Trautmann P (2019) J Math Biol, 79(6-7): 2033-2068.
PMID: 31473798, DOI: 10.1007/s00285-019-01419-3

Scar shape analysis and simulated electrical instabilities in a non-ischemic dilated cardiomyopathy patient cohort.
Balaban G, Halliday BP, Bai W, Porter B, Malvuccio C, Lamata P, Rinaldi CA, Plank G, Rueckert D, Prasad SK, Bishop MJ (2019) PLoS Comput Biol, 15(10): e1007421.
PMID: 31658247, DOI: 10.1371/journal.pcbi.1007421

Pacing in proximity to scar during cardiac resynchronization therapy increases local dispersion of repolarization and susceptibility to ventricular arrhythmogenesis.
Mendonca Costa C, Neic A, Kerfoot E, Porter B, Sieniewicz B, Gould J, Sidhu B, Chen Z, Plank G, Rinaldi CA, Bishop MJ, Niederer SA (2019) Heart Rhythm, 16(10): 1475-1483.
PMID: 30930329, DOI: 10.1016/j.hrthm.2019.03.027

A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data.
Lee AWC, Nguyen UC, Razeghi O, Gould J, Sidhu BS, Sieniewicz B, Behar J, Mafi-Rad M, Plank G, Prinzen FW, Rinaldi CA, Vernooy K, Niederer S (2019) Med Image Anal, 57: 197-213.
PMID: 31326854, DOI: 10.1016/j.media.2019.06.017

Generation of a cohort of whole-torso cardiac models for assessing the utility of a novel computed shock vector efficiency metric for ICD optimisation.
Plancke AM, Connolly A, Gemmell PM, Neic A, McSpadden LC, Whitaker J, O'Neill M, Rinaldi CA, Rajani R, Niederer SA, Plank G, Bishop MJ (2019) Comput Biol Med, 112: 103368.
PMID: 31352217, DOI: 10.1016/j.compbiomed.2019.103368

The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach.
Willemen E, Schreurs R, Huntjens PR, Strik M, Plank G, Vigmond E, Walmsley J, Vernooy K, Delhaas T, Prinzen FW, Lumens J (2019) Front Physiol, 10: 17.
PMID: 30774598, DOI: 10.3389/fphys.2019.00017

Validation of Intramural Wavefront Reconstruction and Estimation of 3D Conduction Velocity.
Good WW, Gillette KK, Bergquist JA, Zenger B, Tate J, Rupp LC, Anderson D, Plank G, MacLeod RS (2019) Comput Cardiol (2010), 46PMID: 32123687, DOI: 10.22489/cinc.2019.420


Fibrosis Microstructure Modulates Reentry in Non-ischemic Dilated Cardiomyopathy: Insights From Imaged Guided 2D Computational Modeling.
Balaban G, Halliday BP, Mendonca Costa C, Bai W, Porter B, Rinaldi CA, Plank G, Rueckert D, Prasad SK, Bishop MJ (2018) Front Physiol, 9 (): 1832.
PMID: 30618838

Assessment of wall stresses and mechanical heart power in the left ventricle: Finite element modeling versus Laplace analysis.
Gsell MAF, Augustin CM, Prassl AJ, Karabelas E, Fernandes JF, Kelm M, Goubergrits L, Kuehne T, Plank G (2018) Int J Numer Method Biomed Eng, 34 (12): e3147.
PMID: 30151998

Personalized computational modeling of left atrial geometry and transmural myofiber architecture.
Fastl TE, Tobon-Gomez C, Crozier A, Whitaker J, Rajani R, McCarthy KP, Sanchez-Quintana D, Ho SY, O'Neill MD, Plank G, Bishop MJ, Niederer SA (2018) Med Image Anal, 47 (): 180-190.
PMID: 29753182

A work flow to build and validate patient specific left atrium electrophysiology models from catheter measurements.
Corrado C, Williams S, Karim R, Plank G, O'Neill M, Niederer S (2018) Med Image Anal, 47 (): 153-163.
PMID: 29753180

Modeling the Electrophysiological Properties of the Infarct Border Zone.
Mendonca Costa C, Plank G, Rinaldi CA, Niederer SA, Bishop MJ (2018) Front Physiol, 9 (): 356.
PMID: 29686626


Highly trabeculated structure of the human endocardium underlies asymmetrical response to low-energy monophasic shocks.
Connolly A, Robson MD, Schneider J, Burton R, Plank G, Bishop MJ (2017) Chaos, 27 (9): 093913.
PMID: 28964115

Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias.
Campos FO, Shiferaw Y, Vigmond EJ, Plank G (2017) Chaos, 27 (9): 093910.
PMID: 28964108

Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model.
Neic A, Campos FO, Prassl AJ, Niederer SA, Bishop MJ, Vigmond EJ, Plank G (2017) J Comput Phys, 346 (): 191-211.
PMID: 28819329

Patient-specific modeling of left ventricular electromechanics as a driver for haemodynamic analysis.
Augustin CM, Crozier A, Neic A, Prassl AJ, Karabelas E, Ferreira da Silva T, Fernandes JF, Campos F, Kuehne T, Plank G (2016) Europace, 18 (suppl 4): iv121-iv129.
PMID: 28011839

Analysis of lead placement optimization metrics in cardiac resynchronization therapy with computational modelling.
Crozier A, Blazevic B, Lamata P, Plank G, Ginks M, Duckett S, Sohal M, Shetty A, Rinaldi CA, Razavi R, Niederer SA, Smith NP (2016) Europace, 18 (suppl 4): iv113-iv120.
PMID: 28011838

Biophysical Modeling to Determine the Optimization of Left Ventricular Pacing Site and AV/VV Delays in the Acute and Chronic Phase of Cardiac Resynchronization Therapy.
Lee AW, Crozier A, Hyde ER, Lamata P, Truong M, Sohal M, Jackson T, Behar JM, Claridge S, Shetty A, Sammut E, Plank G, Rinaldi CA, Niederer S (2017) J Cardiovasc Electrophysiol, 28 (2): 208-215.
PMID: 27885749


Investigating a Novel Activation-Repolarisation Time Metric to Predict Localised Vulnerability to Reentry Using Computational Modelling.
Hill YR, Child N, Hanson B, Wallman M, Coronel R, Plank G, Rinaldi CA, Gill J, Smith NP, Taggart P, Bishop MJ (2016) PLoS One, 11 (3): e0149342.
PMID: 26934736

Anatomically accurate high resolution modeling of human whole heart electromechanics: A strongly scalable algebraic multigrid solver method for nonlinear deformation.
Augustin CM, Neic A, Liebmann M, Prassl AJ, Niederer SA, Haase G, Plank G (2016) J Comput Phys, 305 (): 622-646.
PMID: 26819483

Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour.
Land S, Gurev V, Arens S, Augustin CM, Baron L, Blake R, Bradley C, Castro S, Crozier A, Favino M, Fastl TE, Fritz T, Gao H, Gizzi A, Griffith BE, Hurtado DE, Krause R, Luo X, Nash MP, Pezzuto S, Plank G, Rossi S, Ruprecht D, Seemann G, Smith NP, Sundnes J, Rice JJ, Trayanova N, Wang D, Jenny Wang Z, Niederer SA (2015) Proc Math Phys Eng Sci, 471 (2184): 20150641.
PMID: 26807042

The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study.
Crozier A, Blazevic B, Lamata P, Plank G, Ginks M, Duckett S, Sohal M, Shetty A, Rinaldi CA, Razavi R, Smith NP, Niederer SA (2016) J Mol Cell Cardiol, 96 (): 93-100.
PMID: 26546827

PDE constrained optimization of electrical defibrillation in a 3D ventricular slice geometry.
Chamakuri N, Kunisch K, Plank G (2016) Int J Numer Method Biomed Eng, 32 (4): e02742.
PMID: 26249168


Biophotonic Modelling of Cardiac Optical Imaging.
Bishop MJ, Plank G (2015) Adv Exp Med Biol, 859 (): 367-404.
PMID: 26238061

Beneficial Effect on Cardiac Resynchronization From Left Ventricular Endocardial Pacing Is Mediated by Early Access to High Conduction Velocity Tissue: Electrophysiological Simulation Study.
Hyde ER, Behar JM, Claridge S, Jackson T, Lee AW, Remme EW, Sohal M, Plank G, Razavi R, Rinaldi CA, Niederer SA (2015) Circ Arrhythm Electrophysiol, 8 (5): 1164-72.
PMID: 26136400

Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load.
Campos FO, Shiferaw Y, Prassl AJ, Boyle PM, Vigmond EJ, Plank G (2015) Cardiovasc Res, 107 (1): 175-83.
PMID: 25969391

Local Gradients in Electrotonic Loading Modulate the Local Effective Refractory Period: Implications for Arrhythmogenesis in the Infarct Border Zone.
Connolly A, Trew ML, Smaill BH, Plank G, Bishop MJ (2015) IEEE Trans Biomed Eng, 62 (9): 2251-2259.
PMID: 25872206

Three-dimensional atrial wall thickness maps to inform catheter ablation procedures for atrial fibrillation.
Bishop M, Rajani R, Plank G, Gaddum N, Carr-White G, Wright M, O'Neill M, Niederer S (2016) Europace, 18 (3): 376-83.
PMID: 25842272


Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach.
Bishop MJ, Plank G (2014) Front Physiol, 5 (): 338.
PMID: 25309442

Structural heterogeneity modulates effective refractory period: a mechanism of focal arrhythmia initiation.
Bishop MJ, Connolly A, Plank G (2014) PLoS One, 9 (10): e109754.
PMID: 25291380

Influence of the Purkinje-muscle junction on transmural repolarization heterogeneity.
Walton RD, Martinez ME, Bishop MJ, Hocini M, Haïssaguerre M, Plank G, Bernus O, Vigmond EJ (2014) Cardiovasc Res, 103 (4): 629-40.
PMID: 24997066

Sensitivity and specificity of substrate mapping: an in silico framework for the evaluation of electroanatomical substrate mapping strategies.
Blauer JJ, Swenson D, Higuchi K, Plank G, Ranjan R, Marrouche N, Macleod RS (2014) J Cardiovasc Electrophysiol, 25 (7): 774-80.
PMID: 24762029

Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations.
Costa CM, Hoetzl E, Rocha BM, Prassl AJ, Plank G (2013) Comput Cardiol (2010), 40 (): 373-376.
PMID: 24729986

An efficient finite element approach for modeling fibrotic clefts in the heart.
Costa CM, Campos FO, Prassl AJ, dos Santos RW, Sánchez-Quintana D, Ahammer H, Hofer E, Plank G (2014) IEEE Trans Biomed Eng, 61 (3): 900-10.
PMID: 24557691

Mechanism of reentry induction by a 9-V battery in rabbit ventricles.
Bishop MJ, Burton RA, Kalla M, Nanthakumar K, Plank G, Bub G, Vigmond EJ (2014) Am J Physiol Heart Circ Physiol, 306 (7): H1041-53.
PMID: 24464758

Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis.
Zhou L, Solhjoo S, Millare B, Plank G, Abraham MR, Cortassa S, Trayanova N, O'Rourke B (2014) Circ Arrhythm Electrophysiol, 7 (1): 143-51.
PMID: 24382411

Distribution of decidual natural killer cells and macrophages in the neighbourhood of the trophoblast invasion front: a quantitative evaluation.
Helige C, Ahammer H, Moser G, Hammer A, Dohr G, Huppertz B, Sedlmayr P (2014) Hum Reprod, 29 (1): 8-17.
PMID: 24140594